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Introduction
DermaPepTM MIP, a broad-spectrum antimicrobial peptide, shows a powerful inhibitory activity on S. aureus as well as other bacteria, fungi and mold and helps to protect the skin of AD patients from further microbial attacks. In addition, comparison study with other currently used preservatives shows that DermaPepTM MIP can be a powerful substitute where no toxic preservation system is required.
Function
  • Efficacy of anti-acne
  • Anti-microbial activity
  • Non toxic preservative
Applications

DermaPep™ MIP can be incorporated in cosmetic formulations such as moisturizer, emulsions, oily sera, gels, creams and mist for anti-microbial and preservative purposes.

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Organism Inoculum 2day 7day 14day 21day 28day
Staphylococcus aureus 1x106 ND ND ND ND ND
Escherichia coli 1x106 ND ND ND ND ND
Pseudomonas aeruginosa 1x106 ND ND ND ND ND
Candida albicans 1x106 ND ND ND ND ND
Asperigillus niger 1x106 ND ND ND ND ND

Cream composition for challenge test : Water(88.95 ), Glycerin (3 ), Butylene glycol(2 ), Sorbitan stearate(1 ), Cetyl alcohol(3), Polysorbate 60(1), MIP(0.05), 1,2-Hexanediol(1)

*ND : Not Detected